FLASH is a term used to describe the tissue-sparing effect observed in ultra-high does rate RT. Studies of the FLASH effect have resulted in intense investigation into radiobiology and potential mechanisms of the effect at the molecular level. MOXI is uniquely suited to investigate FLASH, being integrated with one of the only universities with a FLASH-capable linear accelerator devoted exclusively to research use.
Our lab has partnered with the University of Wisconsin Medical Radiation Research Center, IntraOP, and Dartmouth College to acquire a IntraOp Mobetron FLASH linac. Dartmouth College has recently installed an identical Mobetron for consistent, collaborative FLASH studies.
While the bulk of FLASH research is conducted here at UW, the MOXI team has traveled to Dartmouth College, WashU, and the University of Alabama to investigate the FLASH effect on linacs with different characteristics.